Preheat oven to 350°F.
Spray a 9×13 baking dish with nonstick spray. Set aside.
In a large pot, cook the macaroni according to package directions, but cook it for 1 to 2 minutes UNDER al dente. It will continue cooking as it bakes later. Drain the pasta, drizzle the olive oil over it, and toss it to keep it from drying out while you prepare the sauce. Set aside.
In the pot you just cooked the pasta in, melt the butter over medium-low heat. Once butter is melted, add in the flour and whisk for a minute, whisking constantly so you don't burn the flour.
Pour in the 2 cups of whole milk and whisk until all lumps are gone and the mixture is smooth, about 1 minute.
Over medium-high heat, add the 2 cans of evaporated milk, salt, and pepper. Whisk until the mixture is smooth and starts to boil and thicken, about 8-10 minutes. Stir often so it doesn’t burn to the bottom of the pot.
Stir cheeses together in a large bowl.
Stir 4 cups of cheese into the pot and stir until the cheese is melted.
Remove from the heat and stir in the cooked macaroni shells.
Pour into the prepared baking dish. It will look a bit soupy but it will thicken as it cooks.
Sprinkle the remaining one cup of shredded cheese over the top of the mac and cheese.
In a small bowl, mix together the panko bread crumbs and melted butter. Sprinkle over the top of the macaroni and cheese.
Bake for 20 to 25 minutes until the cheese is bubbly and top is golden brown.
Serve hot.